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What is Delta 6A THC?

Definition: Delta 6a10a THC, also known as D6a, delta-3 THC or Δ3-THC, is a naturally-occurring minor cannabinoid and one of seven THC isomers present in varieties of cannabis, including hemp and marijuana. It’s also considered semi-synthetic when producers chemically synthesize it from CBD or delta-9. Chemical synthesis involves altering CBD or THC’s molecular structure using specialized equipment. It’s also mildly intoxicating and can induce a euphoric high similar to delta-8with less potency. Some users report Sativa effects such as energy, mood enhancement, and mental stimulation after consumption.

Chemical formula: Delta 6a10a THC has the chemical formula C21H30O2, meaning it’s made up of 21 carbon atoms, 30 hydrogen atoms, and two oxygen atoms. While this chemical formula is identical to THC and CBD, the arrangement of atoms on their molecular structures is different, causing equally different effects and benefits in your body.

Two enantiomers: There are two enantiomers (optical isomers) of delta 6a10a THC: 1S and 1R. Enantiomers are like two identical screws. They look the same and possess similar physical properties. However, one screw can only turn clockwise and the other anticlockwise. With this analogy in mind, the 1S enantiomer enters the body and screws clockwise, causing a euphoric high similar to delta-8 THC. In contrast, the 1R enantiomer screws anticlockwise, resulting in no intoxicating effects.

Research on delta 6a10a THC

Research on delta 6a10a THC is limited. Very few studies delve into its effects, benefits, or pharmacological activity. However, of the studies we have seen, it’s quite an interesting cannabinoid with some anticonvulsant benefits.

Delta 6a10a THC’s effects begin at a certain dose

According to a 1987 study, a delta 6a10a THC high begins at doses of 8mg or higher in human test subjects, causing a noticeable increase in heart rate and some subtle behavioral differences.

The researchers also note that delta 6a10a THC’s effects are indistinguishable from delta-1 THC, which is the mildest of all THC isomers in terms of potency. What’s interesting about this discovery is many users today claim delta 6a10a THC has similar effects to delta-8 and delta-10, both of which cause a moderate-high in reasonably small doses.

Synthetic delta 6a10a THC is a potential anticonvulsant

EA-1477, a synthetic type of delta 6a10a THC, was tested on canine test subjects in the 1950s. Researchers discovered EA-1477 is a potential anticonvulsant able to abolish electroshock-induced seizures.

EA-1477’s anticonvulsant and seizure-reducing activity is similar to that of THC. However, while THC induces a significant euphoric high, EA-1477 causes dramatically less intoxicating effects.

Both THC and CBD are the primary active compounds in Epidiolex, an FDA-approved prescription medication for the treatment of rare forms of epilepsy, including Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex.

Benefits: What is delta 6a10a THC good for?

While research into delta 6a10a THC’s benefits isn’t as thorough as, say, CBD, we can safely assume it’s they’re similar to THC.

Delta 6a10a THC is a derivative and isomer of THC, meaning they’re almost structurally identical and have similar pharmacological activity in your body when consumed.

With this in mind, we can safely say delta 6a10a THC likely has the same benefits as THC, which include:

  • Pain relief

  • Anti-inflammation

  • Antibacterial

  • Neuroprotection

  • Appetite stimulation

  • Sleep

Effects: How does delta 6a10a THC make you feel?

The effects of delta 6a10a THC are mild intoxication with slight mental impairment and physical sensations. This intoxicating effect is the result of delta 6a10a THC’s ability to bind with cannabinoid 1 (CB1) receptors in your brain and central nervous system.

Those who have tried delta 6a10a THC products experienced a euphoric high similar to a delta-8 high but with roughly 75% less potency. Some users also claim it has Sativa-like effects, including an increase in energy, a noticeable change in mood, and better concentration.

What’s most interesting about delta 6a10a THC’s effects is it might act as a potentiator of other THC isomers. Some users suggest a combination of delta 6a10a THC with delta-8 and delta-10 causes a fairly significant euphoric high.

Is delta 6a10a THC legal?

Technically, yes, delta 6a10a THC is legal and not listed as a controlled substance under federal law, provided it’s sourced from hemp plants carrying no more than 0.3%. If it’s sourced from marijuana carrying more than 0.3% THC, it’s federally illegal and punishable under federal law.

How does delta 6a10a THC compare to other cannabinoids?

Delta 6a10a THC vs delta-10 THC

  • Delta 6a10a THC and delta-10 are both THC isomers present in cannabis and also synthesized from isolated CBD or THC.

  • They’re intoxicating and can induce a high — delta-10 is roughly 60% stronger than delta 6a10a THC.

  • Delta 6a10a THC products are often mislabeled as delta-10 thanks to inaccurate testing.

  • Delta 6a10a THC and delta-10 likely share the same effects and benefits due to being isomers of THC capable of interacting with the same receptor types.

Delta 6a10a THC vs CBD

  • Delta 6a10a THC and CBD have the same chemical formula but they both interact very differently in your body.

  • Delta 6a10a THC binds to CB1 and potentially CB2 receptors, causing mild but noticeable intoxication. CBD doesn’t cause any intoxication, nor does it impair your thinking or judgment.

  • However, like delta 6a10a THC, CBD is psychoactive insofar as activating certain receptors in your brain and central nervous system, causing subtle shifts and changes in mood, behavior, and perception without affecting your thinking or judgment.


Delta 6a10a THC, also referred to as delta-3 THC, isn’t a revolutionary cannabinoid or THC isomer by any means. It has the same effects and benefits as THC, delta-8, and delta-10 but with less euphoria and physical sensations. This lack of euphoria and physical changes might prove beneficial for patients suffering from a range of conditions who dislike the idea of getting high but require a THC treatment.

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