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Advil, Ibuprofen, Excedrin..You have other options.

I want people to understand the short and long term side effects taking over the counter drugs.

I've been in the holistic industry for many years now and wish people had the understanding that there are better options to assist with pain, anxiety, stress, arthritis, headaches, cramps and etc. CBD is extremely beneficial in so many ways and comes from a plant that historically people have been using for thousands of years. My advise is read through some of my blog articles and understand the value in a natural approach to daily body issues.

Below is a breakdown of short and longterm side effects to drugs everyone is taking daily. All information below i got off: , ,


Common Side Effects

These common side effects may not occur in everyone and may be prevented by taking Advil with milk or food. Common side effects of Advil include:

  • Stomach upset

  • Heartburn

  • Nausea and vomiting

  • Diarrhea

  • Gas or bloating

  • Constipation

Serious Side Effects

Advil may also cause rare, but serious, side effects. Many of these serious side effects can be avoided by taking Advil only as recommended. However, taking Advil for too long or taking too much can make these more grave side effects more likely.


Advil and other NSAIDs (with the exception of aspirin) increase a person's chances of developing a heart attack or stroke, and this risk (while present for everyone) is even higher in people who have a history of or risk factors for heart disease.6

Examples of such risk factors include:

  • Diabetes

  • A history of smoking

  • High blood pressure

  • High cholesterol

  • Taking other medications that affect how your blood clots

Seek Emergent Medical Care When taking Advil, if you experience symptoms of a heart attack or stroke, such as chest pain, trouble breathing, sudden weakness or numbness, or difficulty speaking, seek medical attention right away.

Advil and other NSAIDs may also increase a person's blood pressure, and increase their risk of fluid retention and heart failure.


While Advil is associated with a range of mild gastrointestinal side effects, with prolonged use, Advil and other NSAIDs can cause gastrointestinal bleeding and a complication called peptic ulcer disease.

Bleeding and peptic ulcer disease may cause symptoms such as black or bloody stools, abdominal pain, weight loss, heartburn, nausea, and vomiting.

Patients most at risk for serious stomach-related side effects include patients who:

  • Are over 60 years of age

  • Are taking another NSAID in addition to Advil

  • Have a history of stomach ulcers or bleeding problems

  • Drink three or more alcoholic drinks every day while taking Advil

  • Take Advil at a higher dose or for a longer duration than advised

  • Are also taking aspirin, an antiplatelet like Plavix (clopidogrel), a corticosteroid, or an anticoagulant (blood thinner) like coumadin (warfarin)


In rare instances, Advil may lead to liver injury, and this risk is increased with high daily use. Symptoms and signs of liver injury may include:

  • Nausea

  • Tiredness, lack of energy

  • Itchiness

  • An elevation in liver enzymes (seen on a blood test)

  • Abdominal pain (pain in the upper right area of your abdomen)

  • Jaundice (yellowing of the skin and whites of the eyes)

  • Flu-like symptoms


Advil, like other NSAIDs, may also cause kidney injury, and dehydration may increase a person's risk for developing this complication.10 Symptoms of decreased kidney function include increased blood pressure, fluid buildup, urinating less frequently, and dizziness.

Your risk is increased if you are an older adult, take blood pressure medications, and have kidney disease.


Allergic reactions may also occur with taking Advil. Symptoms may include hives, facial swelling, wheezing, rash, skin reddening, blister, and even anaphylactic shock.


Commonly reported side effects of ibuprofen include: hemorrhage, vomiting, anemia, decreased hemoglobin, eosinophilia, and hypertension. Other side effects include: upper gastrointestinal hemorrhage, upper gastrointestinal tract ulcer, dizziness, and dyspepsia. See below for a comprehensive list of adverse effects.

Side effects requiring immediate medical attention

Along with its needed effects, ibuprofen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ibuprofen:

More common

  • Abdominal pain

  • acid or sour stomach

  • belching

  • bloating

  • cloudy urine

  • decrease in amount of urine

  • decrease in urine output or decrease in urine-concentrating ability

  • diarrhea

  • difficulty having a bowel movement (stool)

  • excess air or gas in stomach or intestines

  • full feeling

  • heartburn

  • indigestion

  • itching skin

  • pain or discomfort in chest, upper stomach, or throat

  • pale skin

  • passing gas

  • nausea

  • noisy, rattling breathing

  • rash with flat lesions or small raised lesions on the skin

  • shortness of breath

  • swelling of face, fingers, hands, feet, lower legs, or ankles

  • troubled breathing at rest

  • troubled breathing with exertion

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • vomiting

  • weight gain

Less common

  • Abdominal cramps

  • stomach soreness or discomfort


  • Agitation

  • back, leg, or stomach pains

  • bleeding gums

  • blistering, peeling, loosening of skin

  • blood in urine or stools

  • bloody, black, or tarry stools

  • blurred vision

  • burning feeling in chest or stomach

  • change in vision

  • chest pain

  • chills

  • clay-colored stools

  • coma

  • confusion

  • constipation

  • cough or hoarseness

  • dark urine

  • decreased urine output

  • depression

  • difficulty breathing

  • difficulty swallowing

  • dilated neck veins

  • dizziness

  • dry mouth

  • extreme fatigue

  • fast, irregular, pounding, or racing heartbeat or pulse

  • fever with or without chills

  • frequent urination

  • general body swelling

  • general feeling of tiredness or weakness

  • hair loss, thinning of hair

  • headache

  • hives or welts

  • hostility

  • impaired vision

  • increased blood pressure

  • increased volume of pale, dilute urine

  • irregular breathing

  • irritability

  • itching

  • joint or muscle pain

  • lab results that show problems with liver

  • lethargy

  • light-colored stools

  • loss of appetite

  • lower back or side pain

  • muscle twitching

  • nosebleeds

  • painful or difficult urination

  • pains in stomach, side, or abdomen, possibly radiating to the back

  • pinpoint red spots on skin

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • rash

  • red skin lesions, often with a purple center

  • red, irritated eyes

  • redness of skin

  • seizures

  • severe abdominal pain, cramping, burning

  • severe and continuing nausea

  • sore throat

  • sores, ulcers, or white spots in mouth or on lips

  • stiff neck or back

  • stomach upset

  • stupor

  • swollen or painful glands

  • tenderness in stomach area

  • thirst

  • tightness in chest

  • unpleasant breath odor

  • upper right abdominal pain

  • vomiting of blood

  • vomiting of material that looks like coffee grounds

  • wheezing

  • yellow eyes and skin

Symptoms of overdose

  • Bluish lips or skin

  • difficulty sleeping

  • disorientation

  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

  • drowsiness to profound coma

  • hallucination

  • lightheadedness or fainting

  • mood or other mental changes

  • muscle tremors

  • not breathing

  • rapid, deep breathing

  • restlessness

  • slow or irregular heartbeat

  • stomach cramps

  • sudden fainting

  • sweating

Side effects not requiring immediate medical attention

Some side effects of ibuprofen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Continuing ringing or buzzing or other unexplained noise in ears

  • hearing loss

  • nervousness


  • Crying

  • depersonalization

  • discouragement

  • dry eyes

  • dysphoria

  • euphoria

  • feeling sad or empty

  • lack of appetite

  • loss of interest or pleasure

  • mental depression

  • paranoia

  • quick to react or overreact

  • rapidly changing moods

  • runny nose

  • sleepiness or unusual drowsiness

  • sleeplessness

  • sneezing

  • stuffy nose

  • trouble concentrating

  • trouble sleeping

  • unable to sleep


What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

  • Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.

  • Feeling confused.

  • Feeling very tired or weak.

  • Very bad dizziness or passing out.

  • Ringing in ears.

  • Hearing loss.

  • Very bad headache or if headache is not better after the first dose.

  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

  • Very bad stomach ulcers or bleeding can happen with this drug. Taking it in high doses or for a long time, smoking, or drinking alcohol raises the chance of these side effects. Taking this drug with food will not lower the chance of these effects. Call your doctor or get medical help right away if you get very bad stomach or back pain; black, tarry, or bloody stools; throwing up blood or throw up that looks like coffee grounds; or weight gain or swelling that is not normal.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Stomach pain or heartburn.

  • Upset stomach.


The more commonly reported adverse events may include nausea dyspepsia, nervousness, irritability, sleeplessness, and palpitations.


Acetaminophen (paracetamol):

Frequency not reported: Liver failure


Frequency not reported: Hepatotoxicity, cholestatic hepatitis, aminotransferase elevations


Acetaminophen (paracetamol):

Frequency not reported: Nausea, vomiting


Frequency not reported: Epigastric distress, abdominal discomfort, nausea, vomiting, hemorrhage, peptic ulcers, perforation, esophageal ulcerations, dyspepsia, gastritis


Acetaminophen (paracetamol):

Postmarketing reports: Anaphylaxis, hypersensitivity reactions


Very common (10% or more): Hypersensitivity reactions in asthmatics who are aspirin-sensitive (e.g., with the clinical triad of aspirin sensitivity, bronchial asthma, and nasal polyps)

Frequency not reported: Hypersensitivity reactions include bronchospasm, rhinitis, conjunctivitis, urticaria, angioedema, skin reactions, and anaphylaxis


Acetaminophen (paracetamol):

Very rare (less than 0.01%): Serious skin reactions including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP)


Frequency not reported: Stevens-Johnson syndrome, lichenoid eruption



Frequency not reported: Renal dysfunction, renal failure, increased blood uric acid levels


Acetaminophen (paracetamol):

Frequency not reported: Blood dyscrasias including thrombocytopenia, agranulocytosis


Frequency not reported: Predictable antiplatelet effects, hemorrhage, increased blood fibrinolytic activity, hypoprothrombinemia, thrombocytopenia, thrombocyturia, megaloblastic anemia, pancytopenia, aplastic anemia, ecchymosis



Frequency not reported: Bronchospasm (in patients sensitive to aspirin and other NSAID)


Acetaminophen (paracetamol):

Frequency not reported: Hypotension


Frequency not reported: Salicylate-induced variant angina, ventricular ectopy, conduction abnormalities, and hypotension, particularly during salicylate toxicity


Frequency not reported: Palpitations


Acetaminophen (paracetamol):

Frequency not reported: Hypokalemia, hypoglycemia


Frequency not reported: Dehydration, hyperkalemia, hypoglycemia, sodium and fluid retention, respiratory alkalosis and metabolic acidosis (particularly during salicylate toxicity)

Nervous system

Acetaminophen (paracetamol):

Frequency not reported: Headache, dizziness, dystonia


Frequency not reported: Dizziness, headache


Frequency not reported: Dizziness, tremor


Acetaminophen (paracetamol):

Frequency not reported: Malaise, fatigue


Frequency not reported: Reye's syndrome, tinnitus, temporary hearing loss


Frequency not reported: Fibrocystic breast disease


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7. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

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11. Zimmerman HJ, Maddrey WC "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." Hepatology 22 (1995): 767-73

12. Lee WM "Medical progress: drug-induced hepatotoxicity." N Engl J Med 333 (1995): 1118-27

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14. Perneger TV, Whelton PK, Klag MJ "Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal antiinflammatory drugs." N Engl J Med 331 (1994): 1675-79

15. Shoenfeld Y, Shaklai M, Livni E, Pinkhas J "Thrombocytopenia from acetaminophen." N Engl J Med 303 (1980): 47

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17. Boyle CA, Berkowitz GS, LiVolsi VA, Ort S, Merino MJ, White C, Kelsey JL "Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study." J Natl Cancer Inst 72 (1984): 1015-9

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